Vivaspin Protein Concentration Spin Columns

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Product Details

Vivaspin spin columns are designed for fast, nondenaturing concentration of biological samples by membrane ultrafiltration.

  • High recovery rates  Up to 30-fold concentration of the sample can be achieved, with recovery of the target molecule typically exceeding 95%.
  • Sample protection  the patented Vivaspin dead-stop technology ensures samples cannot be concentrated to dryness and enables direct concentrate recovery.
  • Ease-of-use  one-step sample concentration in a single tube, for minimal sample handling and reduced sample loss.
  • pH compatibility  for a broad range of pH 1 to 9.
  • High flow rates  and minimal membrane blockage through the vertical polyethersulfone PES membrane design.
  • Minimal protein adsorption  thanks to the Vivaspin polycarbonate tube design.
  • Download the Vivaspin protein concentrator data file to learn more and to determine the right MWCO molecular weight cut-off and volume for your enrichment study.

Spin column protein concentration how does it work?

Vivaspin sample concentrators cater to scientists working with sample volumes ranging from 100 _L to 20 mL, with a range of MWCO values from Mr 3000 to 100 000.

An upper compartment contains sample and the lower compartment separated by a semipermeable membrane. Centrifugation is applied to force solvent through the membrane, leaving a more concentrated sample in the upper chamber.

Tip: To maximize recovery of your sample, select a MWCO at least 50% smaller than the molecular size of the target molecule.



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